Claudin 5 antibody (AA 230-303)

Catalog No. ABIN6138692

The Rabbit Polyclonal anti-Claudin 5 antibody has been validated for WB and IF. It is suitable to detect Claudin 5 in samples from Human. There is 1 publication available.

Quick Overview for Claudin 5 antibody (AA 230-303) (ABIN6138692)

Target: Claudin 5 (CLDN5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Claudin 5 Antibody

Binding Specificity: AA 230-303

Sequence: REFYDPSVPV SQKYELGAAL YIGWAATALL MVGGCLLCCG AWVCTGRPDL SFPVKYSAPR RPTATGDYDK KNYV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-303 of human CLDN5 (NP_001124333.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Claudin 5 antibody (ABIN6138692)

Huang, Han, Sun, Zhao, Liu, Yuan, Mao, Peng, Liu, Yin, He: "Kv1.3 channel blocker (ImKTx88) maintains blood-brain barrier in experimental autoimmune encephalomyelitis." in: Cell & bioscience, Vol. 7, pp. 31, (2017) (PubMed).

Target Details for Claudin 5

Target: Claudin 5 (CLDN5)

Alternative Name: CLDN5

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.,CLDN5,AWAL,BEC1,CPETRL1,TMVCF,claudin-5,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN5

Molecular Weight: 23 kDa

Gene ID: 7122

UniProt: O00501

Pathways: Hepatitis C