Clusterin antibody (AA 220-449)

Catalog No. ABIN6138757

The Rabbit Polyclonal anti-Clusterin antibody has been validated for WB, IHC and IF. It is suitable to detect Clusterin in samples from Human.

Quick Overview for Clusterin antibody (AA 220-449) (ABIN6138757)

Target: Clusterin (CLU)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Clusterin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Clusterin Antibody

Binding Specificity: AA 220-449

Sequence: FPKSRIVRSL MPFSPYEPLN FHAMFQPFLE MIHEAQQAMD IHFHSPAFQH PPTEFIREGD DDRTVCREIR HNSTGCLRMK DQCDKCREIL SVDCSTNNPS QAKLRRELDE SLQVAERLTR KYNELLKSYQ WKMLNTSSLL EQLNEQFNWV SRLANLTQGE DQYYLRVTTV ASHTSDSDVP SGVTEVVVKL FDSDPITVTV PVEVSRKNPK FMETVAEKAL QEYRKKHREE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-449 of human Clusterin alpha chain (NP_976084.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Clusterin

Target: Clusterin (CLU)

Alternative Name: CLU

Background: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.,CLU,AAG4,APO-J,APOJ,CLI,CLU1,CLU2,KUB1,NA1/NA2,SGP-2,SGP2,SP-40,TRPM-2,TRPM2,clusterin,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,CLU

Molecular Weight: 32 kDa/48 kDa/52 kDa/53 kDa/57 kDa

Gene ID: 1191

UniProt: P10909

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling