CPE antibody (AA 257-476)

Catalog No. ABIN6138943

This anti-CPE antibody is a Rabbit Polyclonal antibody detecting CPE in WB. Suitable for Human.

Quick Overview for CPE antibody (AA 257-476) (ABIN6138943)

Target: CPE (Carboxypeptidase E (CPE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CPE Antibody

Binding Specificity: AA 257-476

Sequence: PYDETRSGSA HEYSSSPDDA IFQSLARAYS SFNPAMSDPN RPPCRKNDDD SSFVDGTTNG GAWYSVPGGM QDFNYLSSNC FEITVELSCE KFPPEETLKT YWEDNKNSLI SYLEQIHRGV KGFVRDLQGN PIANATISVE GIDHDVTSAK DGDYWRLLIP GNYKLTASAP GYLAITKKVA VPYSPAAGVD FELESFSERK EEEKEELMEW WKMMSETLNF

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 257-476 of human CPE (NP_001864.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CPE

Target: CPE (Carboxypeptidase E (CPE))

Alternative Name: CPE

Background: This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.,CPE,CPH,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,CPE

Molecular Weight: 49 kDa/53 kDa

Gene ID: 1363

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane