CRYGD antibody (AA 18-117)

Catalog No. ABIN6139081

The Rabbit Polyclonal anti-CRYGD antibody has been validated for WB. It is suitable to detect CRYGD in samples from Human.

Quick Overview for CRYGD antibody (AA 18-117) (ABIN6139081)

Target: CRYGD (Crystallin, gamma D (CRYGD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYGD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRYGD Antibody

Binding Specificity: AA 18-117

Sequence: ECSSDHPNLQ PYLSRCNSAR VDSGCWMLYE QPNYSGLQYF LRRGDYADHQ QWMGLSDSVR SCRLIPHSGS HRIRLYERED YRGQMIEFTE DCSCLQDRFR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-117 of human CRYGD (NP_008822.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRYGD

Target: CRYGD (Crystallin, gamma D (CRYGD))

Alternative Name: CRYGD

Background: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.,CRYGD,CACA,CCA3,CCP,CRYG4,CTRCT4,PCC,cry-g-D,Neuroscience,CRYGD

Molecular Weight: 20 kDa

Gene ID: 1421

UniProt: P07320