Cathepsin H antibody (AA 23-335)

Catalog No. ABIN6139232

This Rabbit Polyclonal antibody specifically detects Cathepsin H in WB. It exhibits reactivity toward Human.

Quick Overview for Cathepsin H antibody (AA 23-335) (ABIN6139232)

Target: Cathepsin H (CTSH)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin H antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin H Antibody

Binding Specificity: AA 23-335

Sequence: AELCVNSLEK FHFKSWMSKH RKTYSTEEYH HRLQTFASNW RKINAHNNGN HTFKMALNQF SDMSFAEIKH KYLWSEPQNC SATKSNYLRG TGPYPPSVDW RKKGNFVSPV KNQGACGSCW TFSTTGALES AIAIATGKML SLAEQQLVDC AQDFNNHGCQ GGLPSQAFEY ILYNKGIMGE DTYPYQGKDG YCKFQPGKAI GFVKDVANIT IYDEEAMVEA VALYNPVSFA FEVTQDFMMY RTGIYSSTSC HKTPDKVNHA VLAVGYGEKN GIPYWIVKNS WGPQWGMNGY FLIERGKNMC GLAACASYPI PLV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-335 of human CTSH (NP_004381.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cathepsin H

Target: Cathepsin H (CTSH)

Alternative Name: CTSH

Background: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.,CTSH,ACC-4,ACC-5,ACC4,ACC5,CPSB,Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CTSH

Molecular Weight: 37 kDa

Gene ID: 1512

UniProt: P09668

Pathways: Positive Regulation of Endopeptidase Activity