Dermcidin antibody (AA 20-110)
Quick Overview for Dermcidin antibody (AA 20-110) (ABIN6139437)
Target
See all Dermcidin (DCD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 20-110
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Sequence
- YDPEAASAPG SGNPCHEASA AQKENAGEDP GLARQAPKPR KQRSSLLEKG LDGAKKAVGG LGKLGKDAVE DLESVGKGAV HDVKDVLDSV L
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human DCD (NP_444513.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Dermcidin (DCD)
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Alternative Name
- DCD
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Background
- This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms.,DCD,AIDD,DCD-1,DSEP,HCAP,PIF,dermcidin,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Endocrine & Metabolism,DCD
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Molecular Weight
- 8 kDa/11 kDa/12 kDa
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Gene ID
- 117159
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UniProt
- P81605
Target
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