DDOST antibody (AA 40-300)
Quick Overview for DDOST antibody (AA 40-300) (ABIN6139469)
Target
See all DDOST AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 40-300
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Sequence
- VCASGPRTLV LLDNLNVRET HSLFFRSLKD RGFELTFKTA DDPSLSLIKY GEFLYDNLII FSPSVEDFGG NINVETISAF IDGGGSVLVA ASSDIGDPLR ELGSECGIEF DEEKTAVIDH HNYDISDLGQ HTLIVADTEN LLKAPTIVGK SSLNPILFRG VGMVADPDNP LVLDILTGSS TSYSFFPDKP ITQYPHAVGK NTLLIAGLQA RNNARVIFSG SLDFFSDSFF NSAVQKAAPG SQRYSQTGNY ELAVALSRWV F
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human DDOST (NP_005207.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
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Alternative Name
- DDOST
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Background
- This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.,DDOST,AGER1,CDG1R,GATD6,OKSWcl45,OST,OST48,WBP1,DDOST
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Molecular Weight
- 46 kDa/49 kDa/50 kDa
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Gene ID
- 1650
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UniProt
- P39656
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Pathways
- Cell RedoxHomeostasis
Target
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