DNAI1 antibody (AA 350-699)

Catalog No. ABIN6139690

This Rabbit Polyclonal antibody specifically detects DNAI1 in WB. It exhibits reactivity toward Human.

Quick Overview for DNAI1 antibody (AA 350-699) (ABIN6139690)

Target: DNAI1 (Dynein, Axonemal, Intermediate Chain 1 (DNAI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DNAI1 Antibody

Binding Specificity: AA 350-699

Sequence: VGYGSYDFMK QSRGMLLLYS LKNPSFPEYM FSSNSGVMCL DIHVDHPYLV AVGHYDGNVA IYNLKKPHSQ PSFCSSAKSG KHSDPVWQVK WQKDDMDQNL NFFSVSSDGR IVSWTLVKRK LVHIDVIKLK VEGSTTEVPE GLQLHPVGCG TAFDFHKEID YMFLVGTEEG KIYKCSKSYS SQFLDTYDAH NMSVDTVSWN PYHTKVFMSC SSDWTVKIWD HTIKTPMFIY DLNSAVGDVA WAPYSSTVFA AVTTDGKAHI FDLAINKYEA ICNQPVAAKK NRLTHVQFNL IHPIIIVGDD RGHIISLKLS PNLRKMPKEK KGQEVQKGPA VEIAKLDKLL NLVREVKIKT

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-699 of human DNAI1 (NP_036276.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DNAI1

Target: DNAI1 (Dynein, Axonemal, Intermediate Chain 1 (DNAI1))

Alternative Name: DNAI1

Background: This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.,DNAI1,CILD1,DIC1,ICS1,PCD,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microtubules,Motor Proteins,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Neuron marker,Axon marker,DNAI1

Molecular Weight: 19 kDa/79 kDa

Gene ID: 27019

UniProt: Q9UI46