DUSP10 antibody (AA 1-300)

Catalog No. ABIN6139859

The Rabbit Polyclonal anti-DUSP10 antibody has been validated for WB and IHC. It is suitable to detect DUSP10 in samples from Human.

Quick Overview for DUSP10 antibody (AA 1-300) (ABIN6139859)

Target: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DUSP10 Antibody

Binding Specificity: AA 1-300

Sequence: MPPSPLDDRV VVALSRPVRP QDLNLCLDSS YLGSANPGSN SHPPVIATTV VSLKAANLTY MPSSSGSARS LNCGCSSASC CTVATYDKDN QAQTQAIAAG TTTTAIGTST TCPANQMVNN NENTGSLSPS SGVGSPVSGT PKQLASIKII YPNDLAKKMT KCSKSHLPSQ GPVIIDCRPF MEYNKSHIQG AVHINCADKI SRRRLQQGKI TVLDLISCRE GKDSFKRIFS KEIIVYDENT NEPSRVMPSQ PLHIVLESLK REGKEPLVLK GGLSSFKQNH ENLCDNSLQL QECREVGGGA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DUSP10 (NP_009138.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DUSP10

Target: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Alternative Name: DUSP10

Background: Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.,DUSP10,MKP-5,MKP5,Signal Transduction,Kinase,MAPK-JNK Signaling Pathway,DUSP10

Molecular Weight: 16 kDa/52 kDa

Gene ID: 11221

UniProt: Q9Y6W6