FZD1 antibody (AA 210-320)

Catalog No. ABIN6140836

The Rabbit Polyclonal anti-FZD1 antibody has been validated for WB. It is suitable to detect FZD1 in samples from Human.

Quick Overview for FZD1 antibody (AA 210-320) (ABIN6140836)

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FZD1 Antibody

Binding Specificity: AA 210-320

Sequence: PDTLKCEKFP VHGAGELCVG QNTSDKGTPT PSLLPEFWTS NPQHGGGGHR GGFPGGAGAS ERGKFSCPRA LKVPSYLNYH FLGEKDCGAP CEPTKVYGLM YFGPEELRFS R

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-320 of human FZD1 (NP_003496.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FZD1

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Alternative Name: FZD1

Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.,FZD1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),mTOR Signaling Pathway,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,FZD1

Molecular Weight: 71 kDa

Gene ID: 8321

UniProt: Q9UP38

Pathways: WNT Signaling, Asymmetric Protein Localization