GJB1 antibody (AA 214-283)

Catalog No. ABIN6141104

This Rabbit Polyclonal antibody specifically detects GJB1 in WB. It exhibits reactivity toward Human.

Quick Overview for GJB1 antibody (AA 214-283) (ABIN6141104)

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GJB1 Antibody

Binding Specificity: AA 214-283

Sequence: IRACARRAQR RSNPPSRKGS GFGHRLSPEY KQNEINKLLS EQDGSLKDIL RRSPGTGAGL AEKSDRCSAC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 214-283 of human GJB1 (NP_000157.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GJB1

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Alternative Name: GJB1

Background: This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.,GJB1,CMTX,CMTX1,CX32,Neuroscience,GJB1

Molecular Weight: 32 kDa

Gene ID: 2705

UniProt: P08034

Pathways: Cell-Cell Junction Organization