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Glypican 3 antibody (AA 290-550)

GPC3 Reactivity: Human IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6141306
$589.88
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  • Target See all Glypican 3 (GPC3) Antibodies
    Glypican 3 (GPC3)
    Binding Specificity
    • 28
    • 16
    • 13
    • 10
    • 9
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-550
    Reactivity
    • 183
    • 61
    • 51
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 114
    • 69
    • 2
    Rabbit
    Clonality
    • 95
    • 90
    Polyclonal
    Conjugate
    • 64
    • 14
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glypican 3 antibody is un-conjugated
    Application
    • 107
    • 101
    • 62
    • 59
    • 51
    • 38
    • 17
    • 17
    • 6
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Western Blotting (WB)
    Sequence
    VEIDKYWREY ILSLEELVNG MYRIYDMENV LLGLFSTIHD SIQYVQKNAG KLTTTIGKLC AHSQQRQYRS AYYPEDLFID KKVLKVAHVE HEETLSSRRR ELIQKLKSFI SFYSALPGYI CSHSPVAEND TLCWNGQELV ERYSQKAARN GMKNQFNLHE LKMKGPEPVV SQIIDKLKHI NQLLRTMSMP KGRVLDKNLD EEGFESGDCG DDEDECIGGS GDGMIKVKNQ LRFLAELAYD LDVDDAPGNS QQATPKDNEI S
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 290-550 of human Glypican 3 (GPC3) (GPC3) (NP_004475.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Glypican 3 (GPC3)
    Alternative Name
    GPC3 (GPC3 Products)
    Synonyms
    GPC3, sgb, dgsx, sdys, sgbs, oci-5, sgbs1, DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1, Glypican-3, glypican 3, gpc3, GPC3, Gpc3
    Background
    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.,GPC3,DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS,SGBS1,glypican-3,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Stem Cells,GPC3
    Molecular Weight
    59 kDa/65 kDa/68 kDa
    Gene ID
    2719
    UniProt
    P51654
    Pathways
    Glycosaminoglycan Metabolic Process
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