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Glypican 3 antibody

GPC3 Reactivity: Human, Mouse ICC, FACS, IHC, ELISA, WB Host: Mouse Monoclonal 9C2 unconjugated
Pubmed (2 references)
Catalog No. ABIN969523
$468.60
Plus shipping costs $45.00
0.1 mg
Shipping to: United States
Delivery in 3 to 4 Business Days
  • Target See all Glypican 3 (GPC3) Antibodies
    Glypican 3 (GPC3)
    Reactivity
    • 182
    • 61
    • 50
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 114
    • 68
    • 2
    Mouse
    Clonality
    • 95
    • 89
    Monoclonal
    Conjugate
    • 63
    • 14
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glypican 3 antibody is un-conjugated
    Application
    • 107
    • 100
    • 61
    • 58
    • 50
    • 38
    • 17
    • 16
    • 6
    • 2
    • 2
    • 1
    • 1
    Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human GPC3 expressed in E. coli.
    Clone
    9C2
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Zittermann, Capurro, Shi, Filmus: "Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 6, pp. 1291-301, (2010) (PubMed).

    Takai, Ashihara, Ishiguro, Terashima, Watanabe, Kato, Suzuki: "Involvement of glypican-3 in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma." in: Cancer biology & therapy, Vol. 8, Issue 24, pp. 2329-38, (2010) (PubMed).

  • Target
    Glypican 3 (GPC3)
    Alternative Name
    GPC3 (GPC3 Products)
    Synonyms
    GPC3 antibody, sgb antibody, dgsx antibody, sdys antibody, sgbs antibody, oci-5 antibody, sgbs1 antibody, DGSX antibody, GTR2-2 antibody, MXR7 antibody, OCI-5 antibody, SDYS antibody, SGB antibody, SGBS antibody, SGBS1 antibody, Glypican-3 antibody, glypican 3 antibody, gpc3 antibody, GPC3 antibody, Gpc3 antibody
    Background

    Description: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

    Aliases: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2

    Molecular Weight
    65.5 kDa
    Gene ID
    2719
    HGNC
    2719
    Pathways
    Glycosaminoglycan Metabolic Process
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