GRK4 antibody (AA 359-578)

Catalog No. ABIN6141415

This anti-GRK4 antibody is a Rabbit Polyclonal antibody detecting GRK4 in WB. Suitable for Human.

Quick Overview for GRK4 antibody (AA 359-578) (ABIN6141415)

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GRK4 Antibody

Binding Specificity: AA 359-578

Sequence: NNEKYTFSPD WWGLGCLIYE MIQGHSPFKK YKEKVKWEEV DQRIKNDTEE YSEKFSEDAK SICRMLLTKN PSKRLGCRGE GAAGVKQHPV FKDINFRRLE ANMLEPPFCP DPHAVYCKDV LDIEQFSVVK GIYLDTADED FYARFATGCV SIPWQNEMIE SGCFKDINKS ESEEALPLDL DKNIHTPVSR PNRGFFYRLF RRGGCLTMVP SEKEVEPKQC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 359-578 of human GRK4 (NP_892027.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GRK4

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Alternative Name: GRK4

Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.,GRK4,GPRK2L,GPRK4,GRK4a,IT11,Signal Transduction,Kinase,GRK4

Molecular Weight: 57 kDa/61 kDa/63 kDa/66 kDa

Gene ID: 2868

UniProt: P32298

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling