GTF2A2 antibody (AA 1-109)

Catalog No. ABIN6141490

This anti-GTF2A2 antibody is a Rabbit Polyclonal antibody detecting GTF2A2 in WB. Suitable for Human.

Quick Overview for GTF2A2 antibody (AA 1-109) (ABIN6141490)

Target: GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GTF2A2 Antibody

Binding Specificity: AA 1-109

Sequence: MAYQLYRNTT LGNSLQESLD ELIQSQQITP QLALQVLLQF DKAINAALAQ RVRNRVNFRG SLNTYRFCDN VWTFVLNDVE FREVTELIKV DKVKIVACDG KNTGSNTTE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-109 of human GTF2A2 (NP_004483.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GTF2A2

Target: GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))

Alternative Name: GTF2A2

Background: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A, MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP, MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF, MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).[supplied by OMIM, Mar 2008],GTF2A2,HsT18745,T18745,TF2A2,TFIIA,TFIIA-12,TFIIA-gamma,TFIIAS,Epigenetics & Nuclear Signaling,GTF2A2

Molecular Weight: 12 kDa

Gene ID: 2958

UniProt: P52657