GZMK antibody (AA 27-264)

Catalog No. ABIN6141557

The Rabbit Polyclonal anti-GZMK antibody has been validated for WB. It is suitable to detect GZMK in samples from Human.

Quick Overview for GZMK antibody (AA 27-264) (ABIN6141557)

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GZMK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GZMK Antibody

Binding Specificity: AA 27-264

Sequence: IIGGKEVSPH SRPFMASIQY GGHHVCGGVL IDPQWVLTAA HCQYRFTKGQ SPTVVLGAHS LSKNEASKQT LEIKKFIPFS RVTSDPQSND IMLVKLQTAA KLNKHVKMLH IRSKTSLRSG TKCKVTGWGA TDPDSLRPSD TLREVTVTVL SRKLCNSQSY YNGDPFITKD MVCAGDAKGQ KDSCKGDSGG PLICKGVFHA IVSGGHECGV ATKPGIYTLL TKKYQTWIKS NLVPPHTN

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 27-264 of human GZMK (NP_002095.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GZMK

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Alternative Name: GZMK

Background: This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.,GZMK,TRYP2,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,GZMK

Molecular Weight: 28 kDa

Gene ID: 3003

UniProt: P49863