HAND1 antibody (AA 16-215)

Catalog No. ABIN6141595

This Rabbit Polyclonal antibody specifically detects HAND1 in WB. It exhibits reactivity toward Human.

Quick Overview for HAND1 antibody (AA 16-215) (ABIN6141595)

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAND1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HAND1 Antibody

Binding Specificity: AA 16-215

Sequence: PHPAHPMLHE PFLFGPASRC HQERPYFQSW LLSPADAAPD FPAGGPPPAA AAAATAYGPD ARPGQSPGRL EALGGRLGRR KGSGPKKERR RTESINSAFA ELRECIPNVP ADTKLSKIKT LRLATSYIAY LMDVLAKDAQ SGDPEAFKAE LKKADGGRES KRKRELQQHE GFPPALGPVE KRIKGRTGWP QQVWALELNQ

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 16-215 of human HAND1 (NP_004812.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HAND1

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Alternative Name: HAND1

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.,HAND1,Hxt,Thing1,bHLHa27,eHand,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Stem Cells,Cardiovascular,Angiogenesis,Heart,Cardiogenesis,HAND1

Molecular Weight: 23 kDa

Gene ID: 9421

UniProt: O96004

Pathways: Tube Formation