HNRPLL antibody (AA 250-350)

Catalog No. ABIN6141923

The Rabbit Polyclonal anti-HNRPLL antibody has been validated for WB and IHC. It is suitable to detect HNRPLL in samples from Human.

Quick Overview for HNRPLL antibody (AA 250-350) (ABIN6141923)

Target: HNRPLL (Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRPLL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HNRPLL Antibody

Binding Specificity: AA 250-350

Sequence: IRNDNDSWDY TKPYLGRRDR GKGRQRQAIL GEHPSSFRHD GYGSHGPLLP LPSRYRMGSR DTPELVAYPL PQASSSYMHG GNPSGSVVMV SGLHQLKMNC S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human HNRPLL (NP_612403.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HNRPLL

Target: HNRPLL (Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL))

Alternative Name: HNRNPLL

Background: HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC, MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008],HNRNPLL,HNRPLL,SRRF,Epigenetics & Nuclear Signaling,RNA Binding,HNRNPLL

Molecular Weight: 30 kDa/31 kDa/56 kDa/59 kDa/60 kDa

Gene ID: 92906

UniProt: Q8WVV9