HSP70 1A antibody (AA 500-600)

Catalog No. ABIN6142038

The Rabbit Polyclonal anti-HSP70 1A antibody has been validated for WB, IHC and IF. It is suitable to detect HSP70 1A in samples from Human.

Quick Overview for HSP70 1A antibody (AA 500-600) (ABIN6142038)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP70 1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HSP70 1A Antibody

Binding Specificity: AA 500-600

Sequence: KITITNDKGR LSKEEIERMV QEAEKYKAED EVQRERVSAK NALESYAFNM KSAVEDEGLK GKISEADKKK VLDKCQEVIS WLDANTLAEK DEFEHKRKEL E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500-600 of human HSP70/HSPA1 (NP_005336.3).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Alternative Name: HSPA1A

Background: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.,HSPA1A,HEL-S-103,HSP70-1,HSP70-1A,HSP70.1,HSP70I,HSP72,HSPA1,HSP70,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,HSPA1A

Molecular Weight: 70 kDa

Gene ID: 3303

UniProt: P0DMV8

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process