IKZF3 antibody (AA 280-450)

Catalog No. ABIN6142290

The Rabbit Polyclonal anti-IKZF3 antibody has been validated for WB and IF. It is suitable to detect IKZF3 in samples from Human.

Quick Overview for IKZF3 antibody (AA 280-450) (ABIN6142290)

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-IKZF3 Antibody

Binding Specificity: AA 280-450

Sequence: HCFDVNYNSS YMYEKESELI QTRMMDQAIN NAISYLGAEA LRPLVQTPPA PTSEMVPVIS SMYPIALTRA EMSNGAPQEL EKKSIHLPEK SVPSERGLSP NNSGHDSTDT DSNHEERQNH IYQQNHMVLS RARNGMPLLK EVPRSYELLK PPPICPRDSV KVINKEGEVM D

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 280-450 of human IKZF3 (NP_036613.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IKZF3

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Alternative Name: IKZF3

Background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.,IKZF3,AIO,AIOLOS,ZNFN1A3,Epigenetics & Nuclear Signaling,Transcription Factors,IKZF3

Molecular Weight: 29-58 kDa

Gene ID: 22806

UniProt: Q9UKT9