ING4 antibody (AA 1-190)

Catalog No. ABIN6142452

This Rabbit Polyclonal antibody specifically detects ING4 in WB and IHC. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for ING4 antibody (AA 1-190) (ABIN6142452)

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ING4 Antibody

Binding Specificity: AA 1-190

Sequence: MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKA EIDKLATEYM SSARSLSSEE KLALLKQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESSD YDSSSSKGKK KGRTQKEKKA ARARSKGKNS DEEAPKTAQK KLKLVRTSPE YGMPSVTFGS VHPSDVLDMP

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ING4 (NP_001121054.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-ING4 antibody (ABIN6142452)

Zhang, Zhai, Tang, Cheng, Li, Wang, Zhu: "Quantitative proteome-based systematic identification of SIRT7 substrates." in: Proteomics, Vol. 17, Issue 13-14, (2017) (PubMed).

Target Details for ING4

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Alternative Name: ING4

Background: This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.,ING4,my036,p29ING4,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,ING4

Molecular Weight: 20 kDa/25 kDa/28 kDa

Gene ID: 51147

UniProt: Q9UNL4