INHBB antibody (AA 293-407)

Catalog No. ABIN6142461

This Rabbit Polyclonal antibody specifically detects INHBB in WB. It exhibits reactivity toward Human.

Quick Overview for INHBB antibody (AA 293-407) (ABIN6142461)

Target: INHBB (Inhibin, beta B (INHBB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INHBB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-INHBB Antibody

Binding Specificity: AA 293-407

Sequence: GLECDGRTNL CCRQQFFIDF RLIGWNDWII APTGYYGNYC EGSCPAYLAG VPGSASSFHT AVVNQYRMRG LNPGTVNSCC IPTKLSTMSM LYFDDEYNIV KRDVPNMIVE ECGCA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for INHBB

Target: INHBB (Inhibin, beta B (INHBB))

Alternative Name: INHBB

Background: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.,INHBB,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Immunology & Inflammation,Cytokines,Neuroscience,INHBB

Molecular Weight: 45 kDa

Gene ID: 3625

UniProt: P09529

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion