IRF8 antibody (AA 137-426)

Catalog No. ABIN6142538

This Rabbit Polyclonal antibody specifically detects IRF8 in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for IRF8 antibody (AA 137-426) (ABIN6142538)

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRF8 Antibody

Binding Specificity: AA 137-426

Sequence: ECGRSEIDEL IKEPSVDDYM GMIKRSPSPP EACRSQLLPD WWAQQPSTGV PLVTGYTTYD AHHSAFSQMV ISFYYGGKLV GQATTTCPEG CRLSLSQPGL PGTKLYGPEG LELVRFPPAD AIPSERQRQV TRKLFGHLER GVLLHSSRQG VFVKRLCQGR VFCSGNAVVC KGRPNKLERD EVVQVFDTSQ FFRELQQFYN SQGRLPDGRV VLCFGEEFPD MAPLRSKLIL VQIEQLYVRQ LAEEAGKSCG AGSVMQAPEE PPPDQVFRMF PDICASHQRS FFRENQQITV

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8 (NP_002154.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-IRF8 antibody (ABIN6142538)

Yu, Liu, Zhu, Zhu, Lv, Wang, Wang, Peng: "The Expression of Interferon Regulatory Factor 8 in Human Periapical Lesions." in: Journal of endodontics, Vol. 44, Issue 8, pp. 1276-1282, (2019) (PubMed).

Target Details for IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Alternative Name: IRF8

Background: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.,IRF8,H-ICSBP,ICSBP,ICSBP1,IMD32A,IMD32B,IRF-8,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IRF8

Molecular Weight: 48 kDa

Gene ID: 3394

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin