PHF17 antibody (AA 210-509)

Catalog No. ABIN6142629

The Rabbit Polyclonal anti-PHF17 antibody has been validated for WB and IF. It is suitable to detect PHF17 in samples from Human.

Quick Overview for PHF17 antibody (AA 210-509) (ABIN6142629)

Target: PHF17 (PHD Finger Protein 17 (PHF17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF17 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PHF17 Antibody

Binding Specificity: AA 210-509

Sequence: QSPDGEDGNE MVFCDKCNIC VHQACYGILK VPEGSWLCRT CALGVQPKCL LCPKKGGAMK PTRSGTKWVH VSCALWIPEV SIGSPEKMEP ITKVSHIPSS RWALVCSLCN EKFGASIQCS VKNCRTAFHV TCAFDRGLEM KTILAENDEV KFKSYCPKHS SHRKPEESLG KGAAQENGAP ECSPRNPLEP FASLEQNREE AHRVSVRKQK LQQLEDEFYT FVNLLDVARA LRLPEEVVDF LYQYWKLKRK VNFNKPLITP KKDEEDNLAK REQDVLFRRL QLFTHLRQDL ERVMIDTDTL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of human JADE1 (NP_079176.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:10 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHF17

Target: PHF17 (PHD Finger Protein 17 (PHF17))

Alternative Name: JADE1

Background: Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac, regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling, at least in part, cooperates with NPHP4 in this function.,JADE1,PHF17,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,JADE1

Molecular Weight: 58 kDa/94 kDa/95 kDa

Gene ID: 79960

UniProt: Q6IE81