KCNH1 antibody (AA 813-962)

Catalog No. ABIN6142711

The Rabbit Polyclonal anti-KCNH1 antibody has been validated for WB. It is suitable to detect KCNH1 in samples from Human.

Quick Overview for KCNH1 antibody (AA 813-962) (ABIN6142711)

Target: KCNH1 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNH1 Antibody

Binding Specificity: AA 813-962

Sequence: FKDACGKSED WNKVSKAESM ETLPERTKAS GEATLKKTDS CDSGITKSDL RLDNVGEARS PQDRSPILAE VKHSFYPIPE QTLQATVLEV RHELKEDIKA LNAKMTNIEK QLSEILRILT SRRSSQSPQE LFEISRPQSP ESERDIFGAS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 813-962 of human KCNH1 (NP_002229.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KCNH1

Target: KCNH1 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1))

Alternative Name: KCNH1

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.,KCNH1,EAG,EAG1,Kv10.1,TMBTS,ZLS1,h-eag,hEAG1,Neuroscience,KCNH1

Molecular Weight: 108 kDa/111 kDa

Gene ID: 3756

UniProt: O95259