KIRREL2 antibody (AA 21-220)

Catalog No. ABIN6142894

This Rabbit Polyclonal antibody specifically detects KIRREL2 in WB. It exhibits reactivity toward Human.

Quick Overview for KIRREL2 antibody (AA 21-220) (ABIN6142894)

Target: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIRREL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KIRREL2 Antibody

Binding Specificity: AA 21-220

Sequence: GPSPHFLQQP EDLVVLLGEE ARLPCALGAY WGLVQWTKSG LALGGQRDLP GWSRYWISGN AANGQHDLHI RPVELEDEAS YECQATQAGL RSRPAQLHVL VPPEAPQVLG GPSVSLVAGV PANLTCRSRG DARPTPELLW FRDGVLLDGA TFHQTLLKEG TPGSVESTLT LTPFSHDDGA TFVCRARSQA LPTGRDTAIT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-220 of human KIRREL2 (NP_954649.3).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KIRREL2

Target: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Alternative Name: KIRREL2

Background: This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.,KIRREL2,FILTRIN,NEPH3,NLG1,Cell Biology & Developmental Biology,KIRREL2

Molecular Weight: 23 kDa/61 kDa/67 kDa/75 kDa

Gene ID: 84063

UniProt: Q6UWL6