Keratin 2 antibody (AA 1-220)

Catalog No. ABIN6143025

This Rabbit Polyclonal antibody specifically detects Keratin 2 in WB. It exhibits reactivity toward Human.

Quick Overview for Keratin 2 antibody (AA 1-220) (ABIN6143025)

Target: Keratin 2 (KRT2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Keratin 2 Antibody

Binding Specificity: AA 1-220

Sequence: MSCQISCKSR GRGGGGGGFR GFSSGSAVVS GGSRRSTSSF SCLSRHGGGG GGFGGGGFGS RSLVGLGGTK SISISVAGGG GGFGAAGGFG GRGGGFGGGS SFGGGSGFSG GGFGGGGFGG GRFGGFGGPG GVGGLGGPGG FGPGGYPGGI HEVSVNQSLL QPLNVKVDPE IQNVKAQERE QIKTLNNKFA SFIDKVRFLE QQNQVLQTKW ELLQQMNVGT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Cytokeratin 2e (KRT2) (NP_000414.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Keratin 2

Target: Keratin 2 (KRT2)

Alternative Name: KRT2

Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.,KRT2,CK-2e,K2e,KRT2A,KRT2E,KRTE,keratin 2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Cytokeratin,Keratin,KRT2

Molecular Weight: 65 kDa

Gene ID: 3849

UniProt: P35908