LDLRAP1 antibody (AA 59-308)

Catalog No. ABIN6143131

Product Details anti-LDLRAP1 Antibody

Target: LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))

Binding Specificity: AA 59-308

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDLRAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: EQPKGEELSA AAIKRIVATA KASGKKLQKV TLKVSPRGII LTDNLTNQLI ENVSIYRISY CTADKMHDKV FAYIAQSQHN QSLECHAFLC TKRKMAQAVT LTVAQAFKVA FEFWQVSKEE KEKRDKASQE GGDVLGARQD CTPSLKSLVA TGNLLDLEET AKAPLSTVSA NTTNMDEVPR PQALSGSSVV WELDDGLDEA FSRLAQSRTN PQVLDTGLTA QDMHYAQCLS PVDWDKPDSS GTEQDDLFSF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 59-308 of human LDLRAP1 (NP_056442.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LDLRAP1

Target: LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))

Alternative Name: LDLRAP1 (LDLRAP1 Products)

Background: The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.,LDLRAP1,ARH,ARH1,ARH2,FHCB1,FHCB2,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,LDLRAP1

Molecular Weight: 33 kDa

Gene ID: 26119

UniProt: Q5SW96

Pathways: Lipid Metabolism