LLGL2 antibody (AA 620-819)

Catalog No. ABIN6143262

The Rabbit Polyclonal anti-LLGL2 antibody has been validated for WB and IF. It is suitable to detect LLGL2 in samples from Mouse.

Quick Overview for LLGL2 antibody (AA 620-819) (ABIN6143262)

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LLGL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-LLGL2 Antibody

Binding Specificity: AA 620-819

Sequence: RQVFVKCTLH PSDQLALEGP LSRVKSLKKS LRQSFRRMRR SRVSSHKRRP GGPTGEAQAQ AVNIKAERTG LQNMELAPVQ RKIEARSAED SFTGFVRTLY FADTYLRDSS RHCPSLWAGT NGGTVYAFSL RVPPAERRTD EPVRAEQAKE IQLMHRAPVV GILVLDGHNV PLPEPLEVAH DLSKSPDMQG SHQLLVVSEE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 620-819 of mouse LLGL2 (NP_663413.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LLGL2

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Alternative Name: LLGL2

Background: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.,LLGL2,HGL,Hugl-2,LGL2,Cell Biology & Developmental Biology,Cell Cycle,LLGL2

Molecular Weight: 114 kDa

Gene ID: 217325

Pathways: WNT Signaling