MANEA antibody (AA 30-100)

Catalog No. ABIN6143458

The Rabbit Polyclonal anti-MANEA antibody has been validated for WB. It is suitable to detect MANEA in samples from Human.

Quick Overview for MANEA antibody (AA 30-100) (ABIN6143458)

Target: MANEA (Mannosidase, Endo-alpha (MANEA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MANEA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MANEA Antibody

Binding Specificity: AA 30-100

Sequence: RPNTATFGAP FGLDLLPELH QRTIHLGKNF DFQKSDRINS ETNTKNLKSV EITMKPSKAS ELNLDELPPL N

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human MANEA (NP_078917.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MANEA

Target: MANEA (Mannosidase, Endo-alpha (MANEA))

Alternative Name: MANEA

Background: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008],MANEA,ENDO,hEndo,MANEA

Molecular Weight: 53 kDa

Gene ID: 79694

UniProt: Q5SRI9