MC3R antibody (AA 1-120)

Catalog No. ABIN6143613

This Rabbit Polyclonal antibody specifically detects MC3R in WB. It exhibits reactivity toward Human.

Quick Overview for MC3R antibody (AA 1-120) (ABIN6143613)

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC3R antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MC3R Antibody

Binding Specificity: AA 1-120

Sequence: MNASCCLPSV QPTLPNGSEH LQAPFFSNQS SSAFCEQVFI KPEVFLSLGI VSLLENILVI LAVVRNGNLH SPMYFFLCSL AVADMLVSVS NALETIMIAI VHSDYLTFED QFIQHMDNIF

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human MC3R (NP_063941.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MC3R

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Alternative Name: MC3R

Background: This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.,MC3R,BMIQ9,MC3,MC3-R,OB20,OQTL,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,Neuroscience,Cardiovascular,Heart,Lipids,Fatty Acids,Cardiovascular diseases,Heart disease,MC3R

Molecular Weight: 36 kDa

Gene ID: 4159

UniProt: P41968

Pathways: cAMP Metabolic Process