MESDC2 antibody (AA 1-234)

Catalog No. ABIN6143742

This anti-MESDC2 antibody is a Rabbit Polyclonal antibody detecting MESDC2 in WB. Suitable for Human.

Quick Overview for MESDC2 antibody (AA 1-234) (ABIN6143742)

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MESDC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MESDC2 Antibody

Binding Specificity: AA 1-234

Sequence: MAASRWARKA VVLLCASDLL LLLLLLPPPG SCAAEGSPGT PDESTPPPRK KKKDIRDYND ADMARLLEQW EKDDDIEEGD LPEHKRPSAP VDFSKIDPSK PESILKMTKK GKTLMMFVTV SGSPTEKETE EITSLWQGSL FNANYDVQRF IVGSDRAIFM LRDGSYAWEI KDFLVGQDRC ADVTLEGQVY PGKGGGSKEK NKTKQDKGKK KKEGDLKSRS SKEENRAGNK REDL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human MESDC2 (NP_055969.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MESDC2

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Alternative Name: MESDC2

Background: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.,MESDC2,BOCA,MESD,Cell Biology & Developmental Biology,Stem Cells,Mesenchymal Stem Cells,MESDC2

Molecular Weight: 26 kDa

Gene ID: 23184

UniProt: Q14696