METTL13 antibody (AA 540-699)

Catalog No. ABIN6143756

This Rabbit Polyclonal antibody specifically detects METTL13 in WB. It exhibits reactivity toward Human.

Quick Overview for METTL13 antibody (AA 540-699) (ABIN6143756)

Target: METTL13 (Methyltransferase Like 13 (METTL13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-METTL13 Antibody

Binding Specificity: AA 540-699

Sequence: SQSDRMKVHI ADGLDYIASL AGGGEARPCY DVIMFDVDSK DPTLGMSCPP PAFVEQSFLQ KVKSILTPEG VFILNLVCRD LGLKDSVLAG LKAVFPLLYV RRIEGEVNEI LFCQLHPEQK LATPELLETA QALERTLRKP GRGWDDTYVL SDMLKTVKIV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 540-699 of human METTL13 (NP_057019.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for METTL13

Target: METTL13 (Methyltransferase Like 13 (METTL13))

Alternative Name: METTL13

Background: Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2 at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6.,METTL13,5630401D24Rik,CGI-01,KIAA0859,feat,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,METTL13

Molecular Weight: 44 kDa/61 kDa/68 kDa/72 kDa/78 kDa

Gene ID: 51603

UniProt: Q8N6R0