MTCH2 antibody (AA 30-175)

Catalog No. ABIN6144125

This anti-MTCH2 antibody is a Rabbit Polyclonal antibody detecting MTCH2 in WB, IHC and IF. Suitable for Human.

Quick Overview for MTCH2 antibody (AA 30-175) (ABIN6144125)

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTCH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MTCH2 Antibody

Binding Specificity: AA 30-175

Sequence: VGYEPLPPTI GRNIFGRQVC QLPGLFSYAQ HIASIDGRRG LFTGLTPRLC SGVLGTVVHG KVLQHYQESD KGEELGPGNV QKEVSSSFDH VIKETTREMI ARSAATLITH PFHVITLRSM VQFIGRESKY CGLCDSIITI YREEGI

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-175 of human MTCH2 (NP_055157.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTCH2

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Alternative Name: MTCH2

Background: This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.,MTCH2,HSPC032,MIMP,SLC25A50,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,MTCH2

Molecular Weight: 33 kDa

Gene ID: 23788

UniProt: Q9Y6C9