NANS antibody (AA 260-359)

Catalog No. ABIN6144350

This anti-NANS antibody is a Rabbit Polyclonal antibody detecting NANS in WB. Suitable for Human.

Quick Overview for NANS antibody (AA 260-359) (ABIN6144350)

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NANS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NANS Antibody

Binding Specificity: AA 260-359

Sequence: AELVRSVRLV ERALGSPTKQ LLPCEMACNE KLGKSVVAKV KIPEGTILTM DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-359 of human NANS (NP_061819.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NANS

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Alternative Name: NANS

Background: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.,NANS,HEL-S-100,SAS,SEMDCG,SEMDG,Cancer,Signal Transduction,Endocrine & Metabolism,NANS

Molecular Weight: 40 kDa

Gene ID: 54187

UniProt: Q9NR45