OPRK1 antibody (C-Term)

Catalog No. ABIN6145043

This Rabbit Polyclonal antibody specifically detects OPRK1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for OPRK1 antibody (C-Term) (ABIN6145043)

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-OPRK1 Antibody

Binding Specificity: C-Term

Sequence: GSTSHSTAAL SSYYFCIALG YTNSSLNPIL YAFLDENFKR CFRDFCFPLK MRMERQSTSR VRNTVQDPAY LRDIDGMNKP V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human OPRK1 (NP_000903.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Alternative Name: OPRK1

Background: This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.,OPRK1,K-OR-1,KOR,KOR-1,OPRK,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,OPRK1

Molecular Weight: 33 kDa/42 kDa

Gene ID: 4986

UniProt: P41145