OSTM1 antibody (AA 32-284)

Catalog No. ABIN6145078

The Rabbit Polyclonal anti-OSTM1 antibody has been validated for WB. It is suitable to detect OSTM1 in samples from Human.

Quick Overview for OSTM1 antibody (AA 32-284) (ABIN6145078)

Target: OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSTM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OSTM1 Antibody

Binding Specificity: AA 32-284

Sequence: ALPFGSSPHR VFHDLLSEQQ LLEVEDLSLS LLQGGGLGPL SLPPDLPDLD PECRELLLDF ANSSAELTGC LVRSARPVRL CQTCYPLFQQ VVSKMDNISR AAGNTSESQS CARSLLMADR MQIVVILSEF FNTTWQEANC ANCLTNNSEE LSNSTVYFLN LFNHTLTCFE HNLQGNAHSL LQTKNYSEVC KNCREAYKTL SSLYSEMQKM NELENKAEPG THLCIDVEDA MNITRKLWSR TFNCSVPCSD TVP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 32-284 of human OSTM1 (NP_054747.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OSTM1

Target: OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))

Alternative Name: OSTM1

Background: This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.,OSTM1,GIPN,GL,HSPC019,OPTB5,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Extracellular Matrix,Bone,OSTM1

Molecular Weight: 37 kDa

Gene ID: 28962

UniProt: Q86WC4