P2RX3 antibody (AA 328-397)

Catalog No. ABIN6145111

This Rabbit Polyclonal antibody specifically detects P2RX3 in WB. It exhibits reactivity toward Human.

Quick Overview for P2RX3 antibody (AA 328-397) (ABIN6145111)

Target: P2RX3 (Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-P2RX3 Antibody

Binding Specificity: AA 328-397

Sequence: AFTSVGVGTV LCDIILLNFL KGADQYKAKK FEEVNETTLK IAALTNPVYP SDQTTAEKQS TDSGAFSIGH

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 328-397 of human P2RX3 (NP_002550.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P2RX3

Target: P2RX3 (Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3))

Alternative Name: P2RX3

Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.,P2RX3,P2X3,Cancer,Endocrine & Metabolism,Neuroscience,P2RX3

Molecular Weight: 44 kDa

Gene ID: 5024

UniProt: P56373