PCDHA6 antibody (AA 1-230)

Catalog No. ABIN6145301

The Rabbit Polyclonal anti-PCDHA6 antibody has been validated for WB and IF. It is suitable to detect PCDHA6 in samples from Human.

Quick Overview for PCDHA6 antibody (AA 1-230) (ABIN6145301)

Target: PCDHA6 (Protocadherin alpha 6 (PCDHA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PCDHA6 Antibody

Binding Specificity: AA 1-230

Sequence: MVFTPEDRLG KQCLLLPLLL LAAWKVGSGQ LHYSVPEEAK HGTFVGRIAQ DLGLELAELV PRLFRMASKD REDLLEVNLQ NGILFVNSRI DREELCGRSA ECSIHLEVIV DRPLQVFHVD VEVRDINDNP PLFPVEEQRV LIYESRLPDS VFPLEGASDA DVGSNSILTY KLSSSEYFGL DVKINSDDNK QIGLLLKKSL DREEAPAHNL FLTATDGGKP ELTGTVQLLV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human PCDHA6 (NP_061732.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCDHA6

Target: PCDHA6 (Protocadherin alpha 6 (PCDHA6))

Alternative Name: PCDHA6

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.,PCDHA6,CNR2,CNRN2,CNRS2,CRNR2,PCDH-ALPHA6,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,PCDHA6

Molecular Weight: 75 kDa/86 kDa/102 kDa

Gene ID: 56142

UniProt: Q9UN73