PDGFRL antibody (AA 15-205)

Catalog No. ABIN6145373

The Rabbit Polyclonal anti-PDGFRL antibody has been validated for WB. It is suitable to detect PDGFRL in samples from Human.

Quick Overview for PDGFRL antibody (AA 15-205) (ABIN6145373)

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDGFRL Antibody

Binding Specificity: AA 15-205

Sequence: ALEDVTGQHL PKNKRPKEPG ENRIKPTNKK VKPKIPKMKD RDSANSAPKT QSIMMQVLDK GRFQKPAATL SLLAGQTVEL RCKGSRIGWS YPAYLDTFKD SRLSVKQNER YGQLTLVNST SADTGEFSCW VQLCSGYICR KDEAKTGSTY IFFTEKGELF VPSPSYFDVV YLNPDRQAVV PCRVTVLSAK V

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 15-205 of human PDGFRL (NP_006198.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Alternative Name: PDGFRL

Background: This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.,PDGFRL,PDGRL,PRLTS,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),PDGFRL

Molecular Weight: 41 kDa

Gene ID: 5157

UniProt: Q15198

Pathways: Platelet-derived growth Factor Receptor Signaling