PER1 antibody (AA 1-200)

Catalog No. ABIN6145448

This Rabbit Polyclonal antibody specifically detects PER1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for PER1 antibody (AA 1-200) (ABIN6145448)

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PER1 Antibody

Binding Specificity: AA 1-200

Sequence: MSGPLEGADG GGDPRPGESF CPGGVPSPGP PQHRPCPGPS LADDTDANSN GSSGNESNGH ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE YYQQWSLEEG EPCSMDMSTY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PER1 (NP_002607.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PER1

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Alternative Name: PER1

Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene, however, these variants have not been fully described.,PER1,PER,RIGUI,hPER,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,PER1

Molecular Weight: 91 kDa/136 kDa

Gene ID: 5187

UniProt: O15534

Pathways: Photoperiodism