PIP4K2A antibody (AA 120-350)

Catalog No. ABIN6145673

The Rabbit Polyclonal anti-PIP4K2A antibody has been validated for WB, IHC and IF. It is suitable to detect PIP4K2A in samples from Human.

Quick Overview for PIP4K2A antibody (AA 120-350) (ABIN6145673)

Target: PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIP4K2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PIP4K2A Antibody

Binding Specificity: AA 120-350

Sequence: APLPNDSQAR SGARFHTSYD KRYIIKTITS EDVAEMHNIL KKYHQYIVEC HGITLLPQFL GMYRLNVDGV EIYVIVTRNV FSHRLSVYRK YDLKGSTVAR EASDKEKAKE LPTLKDNDFI NEGQKIYIDD NNKKVFLEKL KKDVEFLAQL KLMDYSLLVG IHDVERAEQE EVECEENDGE EEGESDGTHP VGTPPDSPGN TLNSSPPLAP GEFDPNIDVY GIKCHENSPR K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-350 of human PIP4K2A (NP_005019.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIP4K2A

Target: PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Alternative Name: PIP4K2A

Background: Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.,PIP4K2A,PI5P4KA,PIP5K2A,PIP5KII-alpha,PIP5KIIA,PIPK,Signal Transduction,Kinase,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,PIP4K2A

Molecular Weight: 39 kDa/46 kDa

Gene ID: 5305

UniProt: P48426

Pathways: Inositol Metabolic Process