PRDM2 antibody (AA 1-240)

Catalog No. ABIN6146142

The Rabbit Polyclonal anti-PRDM2 antibody has been validated for WB and IHC. It is suitable to detect PRDM2 in samples from Human.

Quick Overview for PRDM2 antibody (AA 1-240) (ABIN6146142)

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRDM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PRDM2 Antibody

Binding Specificity: AA 1-240

Sequence: MNQNTTEPVA ATETLAEVPE HVLRGLPEEV RLFPSAVDKT RIGVWATKPI LKGKKFGPFV GDKKKRSQVK NNVYMWEVYY PNLGWMCIDA TDPEKGNWLR YVNWACSGEE QNLFPLEINR AIYYKTLKPI APGEELLVWY NGEDNPEIAA AIEEERASAR SKRSSPKSRK GKKKSQENKN KGNKIQDIQL KTSEPDFTSA NMRDSAEGPK EDEEKPSASA LEQPATLQEV ASQEVPPELA

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PRDM2 (NP_036363.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRDM2

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Alternative Name: PRDM2

Background: This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.,PRDM2,HUMHOXY1,KMT8,KMT8A,MTB-ZF,RIZ,RIZ1,RIZ2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Nuclear Receptor Signaling,Cancer,Tumor suppressors,Neuroscience,PRDM2

Molecular Weight: 25 kDa/162 kDa/166 kDa/184 kDa/188 kDa

Gene ID: 7799

UniProt: Q13029