PRODH antibody (AA 321-600)

Catalog No. ABIN6146242

The Rabbit Polyclonal anti-PRODH antibody has been validated for WB. It is suitable to detect PRODH in samples from Human.

Quick Overview for PRODH antibody (AA 321-600) (ABIN6146242)

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRODH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRODH Antibody

Binding Specificity: AA 321-600

Sequence: IDSRTKLSKH LVVPNAQTGQ LEPLLSRFTE EEELQMTRML QRMDVLAKKA TEMGVRLMVD AEQTYFQPAI SRLTLEMQRK FNVEKPLIFN TYQCYLKDAY DNVTLDVELA RREGWCFGAK LVRGAYLAQE RARAAEIGYE DPINPTYEAT NAMYHRCLDY VLEELKHNAK AKVMVASHNE DTVRFALRRM EELGLHPADH QVYFGQLLGM CDQISFPLGQ AGYPVYKYVP YGPVMEVLPY LSRRALENSS LMKGTHRERQ LLWLELLRRL RTGNLFHRPA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human PRODH (NP_057419.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRODH

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Alternative Name: PRODH

Background: This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PRODH,HSPOX2,PIG6,POX,PRODH1,PRODH2,TP53I6,Cancer,Tumor suppressors,p53 pathway,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Amino acid metabolism,PRODH

Molecular Weight: 56 kDa/59 kDa/68 kDa

Gene ID: 5625

UniProt: O43272

Pathways: Response to Water Deprivation, Monocarboxylic Acid Catabolic Process