PTPMT1 antibody (AA 1-201)

Catalog No. ABIN6146436

This anti-PTPMT1 antibody is a Rabbit Polyclonal antibody detecting PTPMT1 in WB. Suitable for Human.

Quick Overview for PTPMT1 antibody (AA 1-201) (ABIN6146436)

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPMT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTPMT1 Antibody

Binding Specificity: AA 1-201

Sequence: MAATALLEAG LARVLFYPTL LYTLFRGKVP GRAHRDWYHR IDPTVLLGAL PLRSLTRQLV QDENVRGVIT MNEEYETRFL CNSSQEWKRL GVEQLRLSTV DMTGIPTLDN LQKGVQFALK YQSLGQCVYV HCKAGRSRSA TMVAAYLIQV HKWSPEEAVR AIAKIRSYIH IRPGQLDVLK EFHKQITARA TKDGTFVISK T

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PTPMT1 (NP_783859.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPMT1

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Alternative Name: PTPMT1

Background: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP to phosphatidylglycerol (PG (By similarity. PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle (By similarity. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production (By similarity. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues (By similarity. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity. May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity.,PTPMT1,DUSP23,MOSP,PLIP,PNAS-129,Signal Transduction,PTPMT1

Molecular Weight: 15 kDa/16 kDa/22 kDa

Gene ID: 114971

UniProt: Q8WUK0

Pathways: Inositol Metabolic Process