PTPRU antibody (AA 1184-1433)

Catalog No. ABIN6146476

This Rabbit Polyclonal antibody specifically detects PTPRU in WB. It exhibits reactivity toward Human.

Quick Overview for PTPRU antibody (AA 1184-1433) (ABIN6146476)

Target: PTPRU (Protein Tyrosine Phosphatase, Receptor Type, U (PTPRU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTPRU Antibody

Binding Specificity: AA 1184-1433

Sequence: IALLPRNRDK NRSMDVLPPD RCLPFLISTD GDSNNYINAA LTDSYTRSAA FIVTLHPLQS TTPDFWRLVY DYGCTSIVML NQLNQSNSAW PCLQYWPEPG RQQYGLMEVE FMSGTADEDL VARVFRVQNI SRLQEGHLLV RHFQFLRWSA YRDTPDSKKA FLHLLAEVDK WQAESGDGRT IVHCLNGGGR SGTFCACATV LEMIRCHNLV DVFFAAKTLR NYKPNMVETM DQYHFCYDVA LEYLEGLESR

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1184-1433 of human PTPRU (NP_001181930.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRU

Target: PTPRU (Protein Tyrosine Phosphatase, Receptor Type, U (PTPRU))

Alternative Name: PTPRU

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.,PTPRU,FMI,PCP-2,PTP,PTP-J,PTP-PI,PTP-RO,PTPPSI,PTPRO,PTPU2,R-PTP-PSI,R-PTP-U,hPTP-J,Signal Transduction,PTPRU

Molecular Weight: 160 kDa/161 kDa/162 kDa

Gene ID: 10076

UniProt: Q92729