Retinoic Acid Receptor gamma antibody (AA 195-454)
Quick Overview for Retinoic Acid Receptor gamma antibody (AA 195-454) (ABIN6146702)
Target
See all Retinoic Acid Receptor gamma (RARG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 195-454
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Sequence
- KAHQETFPSL CQLGKYTTNS SADHRVQLDL GLWDKFSELA TKCIIKIVEF AKRLPGFTGL SIADQITLLK AACLDILMLR ICTRYTPEQD TMTFSDGLTL NRTQMHNAGF GPLTDLVFAF AGQLLPLEMD DTETGLLSAI CLICGDRMDL EEPEKVDKLQ EPLLEALRLY ARRRRPSQPY MFPRMLMKIT DLRGISTKGA ERAITLKMEI PGPMPPLIRE MLENPEMFED DSSQPGPHPN ASSEDEVPGG QGKGGLKSPA
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 195-454 of human RARG (NP_000957.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))
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Alternative Name
- RARG
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Background
- This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RARG,NR1B3,RARC,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Wnt/β-Catenin Signaling Pathway,RARG
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Molecular Weight
- 42 kDa/47 kDa/49 kDa/50 kDa
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Gene ID
- 5916
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UniProt
- P13631
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size
Target
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