RBM5 antibody (AA 1-130)

Catalog No. ABIN6146786

The Rabbit Polyclonal anti-RBM5 antibody has been validated for WB. It is suitable to detect RBM5 in samples from Human.

Quick Overview for RBM5 antibody (AA 1-130) (ABIN6146786)

Target: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RBM5 Antibody

Binding Specificity: AA 1-130

Sequence: MGSDKRVSRT ERSGRYGSII DRDDRDERES RSRRRDSDYK RSSDDRRGDR YDDYRDYDSP ERERERRNSD RSEDGYHSDG DYGEHDYRHD ISDERESKTI MLRGLPITIT ESDIREMMES FEGPQPADVR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBM5 (NP_005769.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RBM5

Target: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Alternative Name: RBM5

Background: This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.,RBM5,G15,H37,LUCA15,RMB5,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,RBM5

Molecular Weight: 14 kDa/16 kDa/17 kDa/92 kDa

Gene ID: 10181

UniProt: P52756

Pathways: Ribonucleoprotein Complex Subunit Organization