RGS10 antibody (AA 1-181)

Catalog No. ABIN6146912

The Rabbit Polyclonal anti-RGS10 antibody has been validated for WB and IHC. It is suitable to detect RGS10 in samples from Human.

Quick Overview for RGS10 antibody (AA 1-181) (ABIN6146912)

Target: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RGS10 Antibody

Binding Specificity: AA 1-181

Sequence: MFNRAVSRLS RKRPPSDIHD SDGSSSSSHQ SLKSTAKWAA SLENLLEDPE GVKRFREFLK KEFSEENVLF WLACEDFKKM QDKTQMQEKA KEIYMTFLSS KASSQVNVEG QSRLNEKILE EPHPLMFQKL QDQIFNLMKY DSYSRFLKSD LFLKHKRTEE EEEDLPDAQT AAKRASRIYN T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human RGS10 (NP_001005339.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RGS10

Target: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Alternative Name: RGS10

Background: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.,RGS10,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,RGS10

Molecular Weight: 19 kDa/20 kDa/21 kDa

Gene ID: 6001

UniProt: O43665

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling