RHOH antibody (AA 1-191)
Quick Overview for RHOH antibody (AA 1-191) (ABIN6146942)
Target
See all RHOH AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-191
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Sequence
- MLSSIKCVLV GDSAVGKTSL LVRFTSETFP EAYKPTVYEN TGVDVFMDGI QISLGLWDTA GNDAFRSIRP LSYQQADVVL MCYSVANHNS FLNLKNKWIG EIRSNLPCTP VLVVATQTDQ REMGPHRASC VNAMEGKKLA QDVRAKGYLE CSALSNRGVQ QVFECAVRTA VNQARRRNRR RLFSINECKI F
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human RHOH (NP_004301.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:10 - 1:100
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- RHOH (Ras Homolog Family Member H (RHOH))
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Alternative Name
- RHOH
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Background
- The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.,RHOH,ARHH,TTF,Signal Transduction,G protein signaling,Signal Transduction,RHOH
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Molecular Weight
- 21 kDa
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Gene ID
- 399
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UniProt
- Q15669
Target
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